Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.Y176_A177delins

c.528_529delinsAA

Surrounding Variants

3 papers

NM_001167.4

p.A177T

c.529G>A

1 paper

NM_001167.4

p.D175G

c.524A>G

1 paper

NM_001167.4

p.H178R

c.533A>G

1 paper

NM_001167.4

p.L179V

c.535C>G

1 paper

NM_001167.4

p.P174A

c.520C>G

1 paper

NM_001167.4

p.L179P

c.536T>C

1 paper

NM_001167.4

p.T180insFs

c.538_539insA

1 paper

NM_001167.4

p.W173*

c.519G>A

1 paper

NM_001167.4

p.T180A

c.538A>G

1 paper

NM_001167.4

p.W173*

c.518G>A

4 papers

NM_001167.4

p.W173G

c.517T>G

3 papers

NM_001167.4

p.Q171*

c.511C>T