Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.G193S

c.577G>A

Surrounding Variants

1 paper

NM_001167.4

p.G193ins2

c.577_578ins6

2 papers

NM_001167.4

p.G195_D196insT

c.583_587ins3

1 paper

NM_001167.4

p.Y191D

c.571T>G

1 paper

NM_001167.4

p.Y190F

c.569A>T

2 papers

NM_001167.4

p.D196G

c.587A>G

5 papers

NM_001167.4

p.L189P

c.566T>C

1 paper

NM_001167.4

p.L189V

c.565C>G

4 papers

NM_001167.4

p.Q197*

c.589C>T

13 papers

NM_001167.4

p.G188E

c.563G>A

6 papers

NM_001167.4

p.V198M

c.592G>A

3 papers

NM_001167.4

p.G188R

c.562G>A

3 papers

NM_001167.4

p.G188R

c.562G>C