Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.C200Fs

c.599delinsGTFs

Surrounding Variants

1 paper

NM_001167.4

p.C200del1

c.598_600delTGC

2 papers

NM_001167.4

p.Q199*

c.595C>T

6 papers

NM_001167.4

p.V198M

c.592G>A

1 paper

NM_001167.4

p.C202C

c.606T>C

4 papers

NM_001167.4

p.G204del1

c.610_611delGGT

14 papers

NM_001167.4

p.C203Y

c.608G>A

1 paper

NM_001167.4

p.C203F

c.608G>T

4 papers

NM_001167.4

p.Q197*

c.589C>T

2 papers

NM_001167.4

p.D196G

c.587A>G

1 paper

NM_001167.4

p.G205del1

c.613_614delGGA

2 papers

NM_001167.4

p.G195_D196insT

c.583_587ins3

1 paper

NM_001167.4

p.K206I

c.617A>T