Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.T274I

c.821C>T

Surrounding Variants

1 paper

NM_001167.4

p.T274delFs

c.821delC

1 paper

NM_001167.4

p.F272fs

c.814_815fs

1 paper

NM_001167.4

p.T271delFs

c.813delT

2 papers

NM_001167.4

p.S278*

c.833C>A

2 papers

NM_001167.4

p.S278*

c.833C>G

1 paper

NM_001167.4

p.S278_V279delFs

c.834_837del4

1 paper

NM_001167.4

p.V279I

c.835G>A

1 paper

NM_001167.4

p.V279D

c.836T>A

1 paper

NM_001167.4

p.V279A

c.836T>C

2 papers

NM_001167.4

p.T271_F272delFs

c.811_815del5

1 paper

NM_001167.4

p.N280H

c.838A>C

1 paper

NM_001167.4

p.N280K

c.840C>A