Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.A291T

c.871G>A

Surrounding Variants

1 paper

NM_001167.4

p.Y290insFs

c.869_870insT

1 paper

NM_001167.4

p.Y290fs

c.868_869fs

1 paper

NM_001167.4

p.L292F

c.876A>C

1 paper

NM_001167.4

p.L292F

c.876A>T

1 paper

NM_001167.4

p.G293S

c.877G>A

1 paper

NM_001167.4

p.G293R

c.877G>C

2 papers

NM_001167.4

p.Y290insFs

c.868_869insT

2 papers

NM_001167.4

p.G293Splc

c.877+1G>A

1 paper

NM_001167.4

p.G293Splc

c.877+3A>G

1 paper

NM_001167.4

p.R286insFs

c.856_857insG

1 paper

NM_001167.4

p.A285del1

c.853_855delGCA

1 paper

NM_001167.4

p.L284_G288del0

c.851_862del12