Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.K297_V298delFs

c.889_892del4

Surrounding Variants

2 papers

NM_001167.4

p.K297*

c.889A>T

7 papers

NM_001167.4

p.D296_V298delFs

c.888_892del5

6 papers

NM_001167.4

p.K297T

c.890A>C

1 paper

NM_001167.4

p.D296fs

c.886_887fs

1 paper

NM_001167.4

p.K297_F301Fs

c.891_902delinsGCCCFs

1 paper

NM_001167.4

p.V298fs

c.892_893fs

2 papers

NM_001167.4

p.K299fs

c.895_896fs

1 paper

NM_001167.4

p.E294A

c.881A>C

1 paper

NM_001167.4

p.E294G

c.881A>G

3 papers

NM_001167.4

p.K299fs

c.895_896fs

1 paper

NM_001167.4

p.C300delFs

c.898delT

1 paper

NM_001167.4

p.C300fs

c.898_899fs