Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

11 papers

NM_001167.4

p.A321G

c.962C>G

Surrounding Variants

10 papers

NM_001167.4

p.W323*

c.968G>A

1 paper

NM_001167.4

p.W323S

c.968G>C

1 paper

NM_001167.4

p.Q319*

c.955C>T

9 papers

NM_001167.4

p.W323*

c.969G>A

1 paper

NM_001167.4

p.E318A

c.953A>C

1 paper

NM_001167.4

p.Y324C

c.971A>G

1 paper

NM_001167.4

p.P325T

c.973C>A

1 paper

NM_001167.4

p.W317*

c.951G>A

1 paper

NM_001167.4

p.W317*

c.950G>A

2 papers

NM_001167.4

p.W317fs

c.949_950fs

2 papers

NM_001167.4

p.W317_A321delFs

c.951_961del11

1 paper

NM_001167.4

p.D315A

c.944A>C