Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

11 papers

NM_001167.4

p.N341delFs

c.1021_1022delAA

Surrounding Variants

1 paper

NM_001167.4

p.N341fs

c.1021_1022fs

2 papers

NM_001167.4

p.N340S

c.1019A>G

1 paper

NM_001167.4

p.N341fs

c.1021_1022fs

1 paper

NM_001167.4

p.N341_I342delFs

c.1023_1026del4

1 paper

NM_001167.4

p.I342fs

c.1024_1025fs

1 paper

NM_001167.4

p.I342delFs

c.1026delT

1 paper

NM_001167.4

p.H343N

c.1027C>A

1 paper

NM_001167.4

p.H343P

c.1028A>C

1 paper

NM_001167.4

p.L344*

c.1031T>A

3 papers

NM_001167.4

p.Q336*

c.1006C>T

1 paper

NM_001167.4

p.T345I

c.1034C>T

2 papers

NM_001167.4

p.H346_S347delFs

c.1038_1041del4