Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.I389_I392del4

c.1165_1175del12

Surrounding Variants

1 paper

NM_001167.4

p.I389V

c.1165A>G

1 paper

NM_001167.4

p.I389F

c.1165A>T

3 papers

NM_001167.4

p.K387_K390del4

c.1159_1169del12

1 paper

NM_001167.4

p.M393_E394del2

c.1177_1181del6

1 paper

NM_001167.4

p.E394_E395insFs

c.1182_1183insT

1 paper

NM_001167.4

p.I397delFs

c.1189delA

1 paper

NM_001167.4

p.M382T

c.1145T>C

1 paper

NM_001167.4

p.K396*

c.1186A>T

1 paper

NM_001167.4

p.R381Q

c.1142G>A

25 papers

NM_001167.4

p.R381*

c.1141C>T

1 paper

NM_001167.4

p.R381delFs

c.1141delC

1 paper

NM_001167.4

p.I397F

c.1189A>T