Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.L410L

c.1230G>A

Surrounding Variants

1 paper

NM_001167.4

p.L410L

c.1228C>T

1 paper

NM_001167.4

p.A412V

c.1235C>T

1 paper

NM_001167.4

p.D413_L414insFs

c.1239_1242dup4

1 paper

NM_001167.4

p.L407_E408ins6

c.1219_1223ins18

1 paper

NM_001167.4

p.V415M

c.1243G>A

1 paper

NM_001167.4

p.V415fs

c.1243_1244fs

2 papers

NM_001167.4

p.S406A

c.1216T>G

1 paper

NM_001167.4

p.N416D

c.1246A>G

1 paper

NM_001167.4

p.Y404C

c.1211A>G

1 paper

NM_001167.4

p.Q418fs

c.1252_1253fs

2 papers

NM_001167.4

p.Q418_K419delFs

c.1253_1256del4

1 paper

NM_001167.4

p.K419fs

c.1255_1256fs