Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001167.4

p.D420_S421delFs

c.1259_1262del4

Surrounding Variants

1 paper

NM_001167.4

p.K419fs

c.1255_1256fs

2 papers

NM_001167.4

p.D420fs

c.1258_1259fs

1 paper

NM_001167.4

p.Q418fs

c.1252_1253fs

2 papers

NM_001167.4

p.Q418_K419delFs

c.1253_1256del4

1 paper

NM_001167.4

p.S421_M422del2

c.1261_1265del6

2 papers

NM_001167.4

p.S421N

c.1262G>A

1 paper

NM_001167.4

p.M422insFs

c.1265_1266ins4

1 paper

NM_001167.4

p.N416D

c.1246A>G

1 paper

NM_001167.4

p.Q423_E425del0

c.1268_1273del6

19 papers

NM_001167.4

p.Q423P

c.1268A>C

1 paper

NM_001167.4

p.V415M

c.1243G>A

1 paper

NM_001167.4

p.V415fs

c.1243_1244fs