Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.L444P

c.1331T>C

Surrounding Variants

2 papers

NM_001167.4

p.R443H

c.1328G>A

3 papers

NM_001167.4

p.R443P

c.1328G>C

1 paper

NM_001167.4

p.E446Q

c.1336G>C

1 paper

NM_001167.4

p.E446A

c.1337A>C

1 paper

NM_001167.4

p.E447*

c.1339G>T

2 papers

NM_001167.4

p.K448_L449insC

c.1342_1346ins3

1 paper

NM_001167.4

p.K448Q

c.1342A>C

1 paper

NM_001167.4

p.L449F

c.1345C>T

1 paper

NM_001167.4

p.E439insFs

c.1315dupG

1 paper

NM_001167.4

p.C450F

c.1349G>T

1 paper

NM_001167.4

p.E438*

c.1312G>T

1 paper

NM_001167.4

p.T437I

c.1310C>T