Varaico: Literature-Extracted Genetic Variants

XPO1

623 papers

RefSeq Summary

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U s...

Pfam Domains

IBN_Naa 46–112UCSCImportin-beta N-terminal domain

Xpo1aa 123–268UCSCExportin 1-like protein

CRM1_repeataa 345–381UCSCChromosome region maintenance or exportin repeat

CRM1_repeat_2aa 405–472UCSCCRM1 / Exportin repeat 2

CRM1_repeat_3aa 485–535UCSCCRM1 / Exportin repeat 3

CRM1_Caa 664–982UCSCCRM1 C terminal

Gene Aliases

HGNC Name

exportin 1

HGNC Alias Symbols

CRM1; CRM-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003400.4

p.F706V

c.2116T>G

Surrounding Variants

1 paper

NM_003400.4

p.P705H

c.2114C>A

1 paper

NM_003400.4

p.A698_A701delFs

c.2094_2101del8

2 papers

NM_003400.4

p.K700E

c.2098A>G

1 paper

NM_003400.4

p.V696E

c.2087T>A

1 paper

NM_003400.4

p.D716Y

c.2146G>T

1 paper

NM_003400.4

p.N695K

c.2085T>G

1 paper

NM_003400.4

p.N695K

c.2085T>A

1 paper

NM_003400.4

p.M717R

c.2150T>G

1 paper

NM_003400.4

p.L718V

c.2152C>G

1 paper

NM_003400.4

p.K722E

c.2164A>G

2 papers

NM_003400.4

p.L724F

c.2170C>T

1 paper

NM_003400.4

p.K686R

c.2057A>G