Varaico: Literature-Extracted Genetic Variants

XPO1

623 papers

RefSeq Summary

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U s...

Pfam Domains

IBN_Naa 46–112UCSCImportin-beta N-terminal domain

Xpo1aa 123–268UCSCExportin 1-like protein

CRM1_repeataa 345–381UCSCChromosome region maintenance or exportin repeat

CRM1_repeat_2aa 405–472UCSCCRM1 / Exportin repeat 2

CRM1_repeat_3aa 485–535UCSCCRM1 / Exportin repeat 3

CRM1_Caa 664–982UCSCCRM1 C terminal

Gene Aliases

HGNC Name

exportin 1

HGNC Alias Symbols

CRM1; CRM-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

10 papers

NM_003400.4

p.D624G

c.1871A>G

Surrounding Variants

1 paper

NM_003400.4

p.I622del1

c.1864_1866delAAT

1 paper

NM_003400.4

p.Q626*

c.1876C>T

1 paper

NM_003400.4

p.Q626R

c.1877A>G

1 paper

NM_003400.4

p.P627H

c.1880C>A

1 paper

NM_003400.4

p.I621V

c.1861A>G

1 paper

NM_003400.4

p.Q628*

c.1882C>T

1 paper

NM_003400.4

p.Q628E

c.1882C>G

1 paper

NM_003400.4

p.N619S

c.1856A>G

1 paper

NM_003400.4

p.Q629_V630Splc

c.1887+1G>T

1 paper

NM_003400.4

p.F610L

c.1830T>G

1 paper

NM_003400.4

p.F610L

c.1830T>A

1 paper

NM_003400.4

p.F610L

c.1828T>C