Varaico: Literature-Extracted Genetic Variants

XPO1

623 papers

RefSeq Summary

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U s...

Pfam Domains

IBN_Naa 46–112UCSCImportin-beta N-terminal domain

Xpo1aa 123–268UCSCExportin 1-like protein

CRM1_repeataa 345–381UCSCChromosome region maintenance or exportin repeat

CRM1_repeat_2aa 405–472UCSCCRM1 / Exportin repeat 2

CRM1_repeat_3aa 485–535UCSCCRM1 / Exportin repeat 3

CRM1_Caa 664–982UCSCCRM1 C terminal

Gene Aliases

HGNC Name

exportin 1

HGNC Alias Symbols

CRM1; CRM-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003400.4

p.H577R

c.1730A>G

Surrounding Variants

1 paper

NM_003400.4

p.H577N

c.1729C>A

1 paper

NM_003400.4

p.M583I

c.1749G>T

1 paper

NM_003400.4

p.M583I

c.1749G>C

1 paper

NM_003400.4

p.M583I

c.1749G>A

2 papers

NM_003400.4

p.E575Splc

c.1724-16A>G

1 paper

NM_003400.4

p.C585F

c.1754G>T

1 paper

NM_003400.4

p.Q593E

c.1777C>G

1 paper

NM_003400.4

p.Q593P

c.1778A>C

1 paper

NM_003400.4

p.K594K

c.1782A>G

1 paper

NM_003400.4

p.C595Y

c.1784G>A

1 paper

NM_003400.4

p.F599F

c.1797C>T

1 paper

NM_003400.4

p.V600I

c.1798G>A