Varaico: Literature-Extracted Genetic Variants

XPO1

623 papers

RefSeq Summary

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U s...

Pfam Domains

IBN_Naa 46–112UCSCImportin-beta N-terminal domain

Xpo1aa 123–268UCSCExportin 1-like protein

CRM1_repeataa 345–381UCSCChromosome region maintenance or exportin repeat

CRM1_repeat_2aa 405–472UCSCCRM1 / Exportin repeat 2

CRM1_repeat_3aa 485–535UCSCCRM1 / Exportin repeat 3

CRM1_Caa 664–982UCSCCRM1 C terminal

Gene Aliases

HGNC Name

exportin 1

HGNC Alias Symbols

CRM1; CRM-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003400.4

p.N567S

c.1700A>G

Surrounding Variants

1 paper

NM_003400.4

p.K568Q

c.1702A>C

1 paper

NM_003400.4

p.K568R

c.1703A>G

1 paper

NM_003400.4

p.K568N

c.1704G>T

1 paper

NM_003400.4

p.K568N

c.1704G>C

1 paper

NM_003400.4

p.V565I

c.1693G>A

1 paper

NM_003400.4

p.T564A

c.1690A>G

12 papers

NM_003400.4

p.E571Q

c.1711G>C

128 papers

NM_003400.4

p.E571K

c.1711G>A

10 papers

NM_003400.4

p.E571V

c.1712A>T

18 papers

NM_003400.4

p.E571G

c.1712A>G

9 papers

NM_003400.4

p.E571A

c.1712A>C

1 paper

NM_003400.4

p.E571delins

c.1711_1712delinsAT