Varaico: Literature-Extracted Genetic Variants

XPO1

623 papers

RefSeq Summary

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U s...

Pfam Domains

IBN_Naa 46–112UCSCImportin-beta N-terminal domain

Xpo1aa 123–268UCSCExportin 1-like protein

CRM1_repeataa 345–381UCSCChromosome region maintenance or exportin repeat

CRM1_repeat_2aa 405–472UCSCCRM1 / Exportin repeat 2

CRM1_repeat_3aa 485–535UCSCCRM1 / Exportin repeat 3

CRM1_Caa 664–982UCSCCRM1 C terminal

Gene Aliases

HGNC Name

exportin 1

HGNC Alias Symbols

CRM1; CRM-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003400.4

p.Y105*

c.315C>G

Surrounding Variants

1 paper

NM_003400.4

p.Y105*

c.315C>A

1 paper

NM_003400.4

p.V106I

c.316G>A

2 papers

NM_003400.4

p.K104delFs

c.312delT

1 paper

NM_003400.4

p.K103_K104delFs

c.309_312del4

2 papers

NM_003400.4

p.K104fs

c.310_311fs

1 paper

NM_003400.4

p.K104R

c.311A>G

1 paper

NM_003400.4

p.K103N

c.309A>T

1 paper

NM_003400.4

p.K103N

c.309A>C

1 paper

NM_003400.4

p.K103fs

c.307_308fs

1 paper

NM_003400.4

p.G108fs

c.322_323fs

1 paper

NM_003400.4

p.G101V

c.302G>T

1 paper

NM_003400.4

p.G101*

c.301G>T