Varaico: Literature-Extracted Genetic Variants

XPO1

623 papers

RefSeq Summary

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U s...

Pfam Domains

IBN_Naa 46–112UCSCImportin-beta N-terminal domain

Xpo1aa 123–268UCSCExportin 1-like protein

CRM1_repeataa 345–381UCSCChromosome region maintenance or exportin repeat

CRM1_repeat_2aa 405–472UCSCCRM1 / Exportin repeat 2

CRM1_repeat_3aa 485–535UCSCCRM1 / Exportin repeat 3

CRM1_Caa 664–982UCSCCRM1 C terminal

Gene Aliases

HGNC Name

exportin 1

HGNC Alias Symbols

CRM1; CRM-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003400.4

p.T75M

c.224C>T

Surrounding Variants

1 paper

NM_003400.4

p.Q71_M73del0

c.213_218del6

1 paper

NM_003400.4

p.T75T

c.225G>A

1 paper

NM_003400.4

p.T75S

c.223A>T

1 paper

NM_003400.4

p.S70_M73insFs

c.210_217dup8

1 paper

NM_003400.4

p.M73T

c.218T>C

4 papers

NM_003400.4

p.Q71L

c.212A>T

2 papers

NM_003400.4

p.Q71*

c.211C>T

1 paper

NM_003400.4

p.S70delFs

c.208delA

1 paper

NM_003400.4

p.T65_I66delins

c.195_197delinsTCA

1 paper

NM_003400.4

p.T65T

c.195A>T

1 paper

NM_003400.4

p.D64E

c.192C>G

1 paper

NM_003400.4

p.D64N

c.190G>A