Varaico: Literature-Extracted Genetic Variants

XPO1

623 papers

RefSeq Summary

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U s...

Pfam Domains

IBN_Naa 46–112UCSCImportin-beta N-terminal domain

Xpo1aa 123–268UCSCExportin 1-like protein

CRM1_repeataa 345–381UCSCChromosome region maintenance or exportin repeat

CRM1_repeat_2aa 405–472UCSCCRM1 / Exportin repeat 2

CRM1_repeat_3aa 485–535UCSCCRM1 / Exportin repeat 3

CRM1_Caa 664–982UCSCCRM1 C terminal

Gene Aliases

HGNC Name

exportin 1

HGNC Alias Symbols

CRM1; CRM-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003400.4

p.H56N

c.166C>A

Surrounding Variants

1 paper

NM_003400.4

p.P57S

c.169C>T

1 paper

NM_003400.4

p.D58E

c.174T>A

1 paper

NM_003400.4

p.W60C

c.180G>T

1 paper

NM_003400.4

p.W60C

c.180G>C

2 papers

NM_003400.4

p.L50Q

c.149T>A

1 paper

NM_003400.4

p.T61T

c.183A>T

1 paper

NM_003400.4

p.R62K

c.185G>A

1 paper

NM_003400.4

p.E48insFs

c.143_144insA

1 paper

NM_003400.4

p.V63L

c.187G>C

1 paper

NM_003400.4

p.V63I

c.187G>A

1 paper

NM_003400.4

p.E48D

c.144A>T

1 paper

NM_003400.4

p.E48D

c.144A>C