Varaico: Literature-Extracted Genetic Variants

XPO1

623 papers

RefSeq Summary

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U s...

Pfam Domains

IBN_Naa 46–112UCSCImportin-beta N-terminal domain

Xpo1aa 123–268UCSCExportin 1-like protein

CRM1_repeataa 345–381UCSCChromosome region maintenance or exportin repeat

CRM1_repeat_2aa 405–472UCSCCRM1 / Exportin repeat 2

CRM1_repeat_3aa 485–535UCSCCRM1 / Exportin repeat 3

CRM1_Caa 664–982UCSCCRM1 C terminal

Gene Aliases

HGNC Name

exportin 1

HGNC Alias Symbols

CRM1; CRM-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003400.4

p.V32E

c.95T>A

Surrounding Variants

1 paper

NM_003400.4

p.V32A

c.95T>C

5 papers

NM_003400.4

p.V31V

c.93G>A

1 paper

NM_003400.4

p.N33K

c.99T>A

1 paper

NM_003400.4

p.N30S

c.89A>G

2 papers

NM_003400.4

p.D29_N30delFs

c.85_88del4

1 paper

NM_003400.4

p.D29fs

c.85_86fs

1 paper

NM_003400.4

p.L35L

c.103T>C

1 paper

NM_003400.4

p.D29fs

c.85_86fs

1 paper

NM_003400.4

p.L28S

c.83T>C

1 paper

NM_003400.4

p.Y36C

c.107A>G

1 paper

NM_003400.4

p.L27I

c.79T>A

1 paper

NM_003400.4

p.N26S

c.77A>G