Varaico: Literature-Extracted Genetic Variants

XPO1

623 papers

RefSeq Summary

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U s...

Pfam Domains

IBN_Naa 46–112UCSCImportin-beta N-terminal domain

Xpo1aa 123–268UCSCExportin 1-like protein

CRM1_repeataa 345–381UCSCChromosome region maintenance or exportin repeat

CRM1_repeat_2aa 405–472UCSCCRM1 / Exportin repeat 2

CRM1_repeat_3aa 485–535UCSCCRM1 / Exportin repeat 3

CRM1_Caa 664–982UCSCCRM1 C terminal

Gene Aliases

HGNC Name

exportin 1

HGNC Alias Symbols

CRM1; CRM-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003400.4

p.Q15Q

c.45G>A

Surrounding Variants

1 paper

NM_003400.4

p.R14fs

c.40_41fs

1 paper

NM_003400.4

p.R14insFs

c.40_41insCC

1 paper

NM_003400.4

p.A9_R14delFs

c.27_40del14

1 paper

NM_003400.4

p.L16_L17delins

c.47_49delinsTAT

1 paper

NM_003400.4

p.A12V

c.35C>T

1 paper

NM_003400.4

p.A12G

c.35C>G

1 paper

NM_003400.4

p.D10fs

c.28_29fs

1 paper

NM_003400.4

p.A9V

c.26C>T

1 paper

NM_003400.4

p.A9G

c.26C>G

1 paper

NM_003400.4

p.K22E

c.64A>G

1 paper

NM_003400.4

p.A9S

c.25G>T

1 paper

NM_003400.4

p.A9T

c.25G>A