Varaico: Literature-Extracted Genetic Variants

XPO1

623 papers

RefSeq Summary

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U s...

Pfam Domains

IBN_Naa 46–112UCSCImportin-beta N-terminal domain

Xpo1aa 123–268UCSCExportin 1-like protein

CRM1_repeataa 345–381UCSCChromosome region maintenance or exportin repeat

CRM1_repeat_2aa 405–472UCSCCRM1 / Exportin repeat 2

CRM1_repeat_3aa 485–535UCSCCRM1 / Exportin repeat 3

CRM1_Caa 664–982UCSCCRM1 C terminal

Gene Aliases

HGNC Name

exportin 1

HGNC Alias Symbols

CRM1; CRM-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003400.4

p.A3G

c.8C>G

Surrounding Variants

1 paper

NM_003400.4

p.A3S

c.7G>T

1 paper

NM_003400.4

p.A3P

c.7G>C

1 paper

NM_003400.4

p.A3T

c.7G>A

1 paper

NM_003400.4

p.I4I

c.12T>A

1 paper

NM_003400.4

p.P2S

c.4C>T

1 paper

NM_003400.4

p.M1del1

c.1_2delCAT

1 paper

NM_003400.4

p.M1fs

c.1_2fs

1 paper

NM_003400.4

p.M1_P2insFs

c.3_4insA

1 paper

NM_003400.4

p.M1delFs

c.2delA

1 paper

NM_003400.4

p.M1insFs

c.2_3insCT

1 paper

NM_003400.4

p.M1T

c.2T>C

1 paper

NM_003400.4

p.M1V

c.1A>G