Varaico: Literature-Extracted Genetic Variants

XRCC1

1,763 papers

RefSeq Summary

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase ...

Pfam Domains

XRCC1_Naa 1–149UCSCXRCC1 N terminal domain

BRCTaa 315–390UCSCBRCA1 C Terminus (BRCT) domain

BRCTaa 538–616UCSCBRCA1 C Terminus (BRCT) domain

Gene Aliases

HGNC Name

X-ray repair cross complementing 1

HGNC Previous Name

X-ray repair complementing defective repair in Chinese hamster cells 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

15 papers

NM_006297.3

p.T304A

c.910A>G

Surrounding Variants

1 paper

NM_006297.3

p.G303V

c.908G>T

1 paper

NM_006297.3

p.T304T

c.912C>T

2 papers

NM_006297.3

p.E305D

c.915G>C

1 paper

NM_006297.3

p.E302G

c.905A>G

1 paper

NM_006297.3

p.P306H

c.917C>A

1 paper

NM_006297.3

p.G301E

c.902G>A

1 paper

NM_006297.3

p.P306P

c.918C>T

1 paper

NM_006297.3

p.R308*

c.922C>T

1 paper

NM_006297.3

p.R300*

c.898C>T

4 papers

NM_006297.3

p.P309S

c.925C>T

1 paper

NM_006297.3

p.P299T

c.895C>A

2 papers

NM_006297.3

p.K298N

c.894A>T