Varaico: Literature-Extracted Genetic Variants

XRCC1

1,763 papers

RefSeq Summary

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase ...

Pfam Domains

XRCC1_Naa 1–149UCSCXRCC1 N terminal domain

BRCTaa 315–390UCSCBRCA1 C Terminus (BRCT) domain

BRCTaa 538–616UCSCBRCA1 C Terminus (BRCT) domain

Gene Aliases

HGNC Name

X-ray repair cross complementing 1

HGNC Previous Name

X-ray repair complementing defective repair in Chinese hamster cells 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_006297.3

p.P206P

c.618A>G

Surrounding Variants

1 paper

NM_006297.3

p.P206P

c.618A>T

3 papers

NM_006297.3

p.P206L

c.617C>T

1 paper

NM_006297.3

p.P206A

c.616C>G

1 paper

NM_006297.3

p.P206T

c.616C>A

1 paper

NM_006297.3

p.G208A

c.623G>C

1 paper

NM_006297.3

p.P209A

c.625C>G

5 papers

NM_006297.3

p.A203A

c.609C>T

1 paper

NM_006297.3

p.T202T

c.606A>G

2 papers

NM_006297.3

p.Y211C

c.632A>G

1 paper

NM_006297.3

p.A212P

c.634G>C

1 paper

NM_006297.3

p.A212E

c.635C>A

1 paper

NM_006297.3

p.A213G

c.638C>G