Varaico: Literature-Extracted Genetic Variants

XRCC3

1,061 papers

RefSeq Summary

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complem...

Pfam Domains

HHH_XRCC3_RpoAaa 3–57UCSCXRCC3/RpoA-like, helix-hairpin-helix domain

Rad51aa 77–340UCSCRad51

Gene Aliases

HGNC Name

X-ray repair cross complementing 3

HGNC Previous Name

X-ray repair complementing defective repair in Chinese hamster cells 3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005432.4

p.Y330*

c.990C>G

Surrounding Variants

1 paper

NM_005432.4

p.Y330*

c.990C>A

1 paper

NM_005432.4

p.T331M

c.992C>T

1 paper

NM_005432.4

p.S333I

c.998G>T

1 paper

NM_005432.4

p.S327fs

c.979_980fs

1 paper

NM_005432.4

p.E335K

c.1003G>A

22 papers

NM_005432.4

p.S326C

c.977C>G

1 paper

NM_005432.4

p.S326fs

c.976_977fs

1 paper

NM_005432.4

p.P325P

c.975C>G

1 paper

NM_005432.4

p.P325S

c.973C>T

1 paper

NM_005432.4

p.V337E

c.1010T>A

1 paper

NM_005432.4

p.V337insFs

c.1010dupT

1 paper

NM_005432.4

p.R338fs

c.1012_1013fs