Varaico: Literature-Extracted Genetic Variants

XRCC3

1,061 papers

RefSeq Summary

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complem...

Pfam Domains

HHH_XRCC3_RpoAaa 3–57UCSCXRCC3/RpoA-like, helix-hairpin-helix domain

Rad51aa 77–340UCSCRad51

Gene Aliases

HGNC Name

X-ray repair cross complementing 3

HGNC Previous Name

X-ray repair complementing defective repair in Chinese hamster cells 3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005432.4

p.L293L

c.879G>A

Surrounding Variants

1 paper

NM_005432.4

p.L297P

c.890T>C

1 paper

NM_005432.4

p.A289P

c.865G>C

1 paper

NM_005432.4

p.W288R

c.862T>A

1 paper

NM_005432.4

p.R300W

c.898C>T

5 papers

NM_005432.4

p.T287A

c.859A>G

3 papers

NM_005432.4

p.R302H

c.905G>A

1 paper

NM_005432.4

p.R302fs

c.904_905fs

1 paper

NM_005432.4

p.E303G

c.908A>G

1 paper

NM_005432.4

p.E304*

c.910G>T

1 paper

NM_005432.4

p.A283V

c.848C>T

1 paper

NM_005432.4

p.P282fs

c.844_845fs

1 paper

NM_005432.4

p.P282delFs

c.845delG