Varaico: Literature-Extracted Genetic Variants

XRCC3

1,061 papers

RefSeq Summary

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complem...

Pfam Domains

HHH_XRCC3_RpoAaa 3–57UCSCXRCC3/RpoA-like, helix-hairpin-helix domain

Rad51aa 77–340UCSCRad51

Gene Aliases

HGNC Name

X-ray repair cross complementing 3

HGNC Previous Name

X-ray repair complementing defective repair in Chinese hamster cells 3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005432.4

p.E261fs

c.781_782fs

Surrounding Variants

1 paper

NM_005432.4

p.E261D

c.783G>C

1 paper

NM_005432.4

p.E261delFs

c.782_783delCT

1 paper

NM_005432.4

p.E264K

c.790G>A

2 papers

NM_005432.4

p.Q266*

c.796C>T

1 paper

NM_005432.4

p.G267A

c.800G>C

1 paper

NM_005432.4

p.G267D

c.800G>A

1 paper

NM_005432.4

p.G267_A268del2

c.799_803del6

1 paper

NM_005432.4

p.P272S

c.814C>T

1 paper

NM_005432.4

p.P272T

c.814C>A

1 paper

NM_005432.4

p.P272Q

c.815C>A

1 paper

NM_005432.4

p.Q258_V259Splc

c.775-38C>T

1 paper

NM_005432.4

p.G274Splc

c.821+5G>A