Varaico: Literature-Extracted Genetic Variants

XRCC3

1,061 papers

RefSeq Summary

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complem...

Pfam Domains

HHH_XRCC3_RpoAaa 3–57UCSCXRCC3/RpoA-like, helix-hairpin-helix domain

Rad51aa 77–340UCSCRad51

Gene Aliases

HGNC Name

X-ray repair cross complementing 3

HGNC Previous Name

X-ray repair complementing defective repair in Chinese hamster cells 3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005432.4

p.I179_F180insFs

c.537_538insC

Surrounding Variants

1 paper

NM_005432.4

p.I181V

c.541A>G

1 paper

NM_005432.4

p.Q178R

c.533A>G

1 paper

NM_005432.4

p.E182K

c.544G>A

1 paper

NM_005432.4

p.V184M

c.550G>A

3 papers

NM_005432.4

p.A185A

c.555C>T

1 paper

NM_005432.4

p.D186fs

c.556_557fs

2 papers

NM_005432.4

p.R174*

c.520C>T

1 paper

NM_005432.4

p.D186delFs

c.558delA

1 paper

NM_005432.4

p.L173F

c.517C>T

1 paper

NM_005432.4

p.Q171*

c.511C>T

1 paper

NM_005432.4

p.Q171K

c.511C>A

1 paper

NM_005432.4

p.L169P

c.506T>C