Varaico: Literature-Extracted Genetic Variants

XRCC3

1,061 papers

RefSeq Summary

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complem...

Pfam Domains

HHH_XRCC3_RpoAaa 3–57UCSCXRCC3/RpoA-like, helix-hairpin-helix domain

Rad51aa 77–340UCSCRad51

Gene Aliases

HGNC Name

X-ray repair cross complementing 3

HGNC Previous Name

X-ray repair complementing defective repair in Chinese hamster cells 3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_005432.4

p.R150C

c.448C>T

Surrounding Variants

2 papers

NM_005432.4

p.Q152K

c.454C>A

1 paper

NM_005432.4

p.P147P

c.441G>A

1 paper

NM_005432.4

p.P147L

c.440C>T

1 paper

NM_005432.4

p.A145A

c.435C>T

1 paper

NM_005432.4

p.M155V

c.463A>G

1 paper

NM_005432.4

p.A156T

c.466G>A

1 paper

NM_005432.4

p.E143G

c.428A>G

1 paper

NM_005432.4

p.E143A

c.428A>C

1 paper

NM_005432.4

p.P159S

c.475C>T

1 paper

NM_005432.4

p.P159L

c.476C>T

1 paper

NM_005432.4

p.I140S

c.419T>G

1 paper

NM_005432.4

p.I140T

c.419T>C