Varaico: Literature-Extracted Genetic Variants

XRCC3

1,061 papers

RefSeq Summary

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complem...

Pfam Domains

HHH_XRCC3_RpoAaa 3–57UCSCXRCC3/RpoA-like, helix-hairpin-helix domain

Rad51aa 77–340UCSCRad51

Gene Aliases

HGNC Name

X-ray repair cross complementing 3

HGNC Previous Name

X-ray repair complementing defective repair in Chinese hamster cells 3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005432.4

p.T52delFs

c.155delG

Surrounding Variants

1 paper

NM_005432.4

p.T52T

c.156G>C

2 papers

NM_005432.4

p.T52M

c.155C>T

1 paper

NM_005432.4

p.T52A

c.154A>G

1 paper

NM_005432.4

p.A53A

c.159C>G

1 paper

NM_005432.4

p.R51I

c.152G>T

1 paper

NM_005432.4

p.L50fs

c.148_149fs

1 paper

NM_005432.4

p.H56Y

c.166C>T

1 paper

NM_005432.4

p.R58W

c.172C>T

1 paper

NM_005432.4

p.V46A

c.137T>C

24 papers

NM_005432.4

p.E45D

c.135G>C

1 paper

NM_005432.4

p.E45G

c.134A>G

1 paper

NM_005432.4

p.E45A

c.134A>C