Varaico: Literature-Extracted Genetic Variants

XRCC3

1,061 papers

RefSeq Summary

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complem...

Pfam Domains

HHH_XRCC3_RpoAaa 3–57UCSCXRCC3/RpoA-like, helix-hairpin-helix domain

Rad51aa 77–340UCSCRad51

Gene Aliases

HGNC Name

X-ray repair cross complementing 3

HGNC Previous Name

X-ray repair complementing defective repair in Chinese hamster cells 3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005432.4

p.P44delFs

c.131_132delGG

Surrounding Variants

3 papers

NM_005432.4

p.E45K

c.133G>A

1 paper

NM_005432.4

p.E45G

c.134A>G

1 paper

NM_005432.4

p.E45A

c.134A>C

24 papers

NM_005432.4

p.E45D

c.135G>C

1 paper

NM_005432.4

p.V46A

c.137T>C

1 paper

NM_005432.4

p.S42S

c.126C>A

2 papers

NM_005432.4

p.S42F

c.125C>T

1 paper

NM_005432.4

p.N40K

c.120C>A

1 paper

NM_005432.4

p.L50fs

c.148_149fs

1 paper

NM_005432.4

p.T39S

c.116C>G

1 paper

NM_005432.4

p.R51I

c.152G>T

1 paper

NM_005432.4

p.L38L

c.112C>T