Varaico: Literature-Extracted Genetic Variants

XRCC4

333 papers

RefSeq Summary

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous ...

Pfam Domains

XRCC4aa 17–114UCSCXRCC4 N-terminal domain

XRCC4_CCaa 117–194UCSCXRCC4 coiled-coil

XRCC4_Caa 222–334UCSCXRCC4 C-terminal region

Gene Aliases

HGNC Name

X-ray repair cross complementing 4

HGNC Alias Symbol

hXRCC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003401.5

p.S23A

c.67T>G

Surrounding Variants

1 paper

NM_003401.5

p.Q21E

c.61C>G

1 paper

NM_003401.5

p.T27P

c.79A>C

1 paper

NM_003401.5

p.G31A

c.92G>C

1 paper

NM_003401.5

p.G31G

c.93T>C

1 paper

NM_003401.5

p.E13*

c.37G>T

2 papers

NM_003401.5

p.S12C

c.35C>G

1 paper

NM_003401.5

p.S12T

c.34T>A

2 papers

NM_003401.5

p.S12A

c.34T>G

1 paper

NM_003401.5

p.I34T

c.101T>C

1 paper

NM_003401.5

p.V11I

c.31G>A

2 papers

NM_003401.5

p.H9fs

c.25_26fs

5 papers

NM_003401.5

p.H9fs

c.25_26fs