Varaico: Literature-Extracted Genetic Variants

Gene:XRN2
Variant:p.T439A

XRN2

73 papers

RefSeq Summary

This gene encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isofo...

Pfam Domains

XRN_Naa 1–254UCSCXRN 5'-3' exonuclease N-terminus
XRN_Maa 325–786UCSCXrn1 helical domain

Gene Aliases

HGNC Name

5'-3' exoribonuclease 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_012255.5
p.T439A
c.1315A>G
Surrounding Variants
1 paper
NM_012255.5
p.T439P
c.1315A>C
1 paper
NM_012255.5
p.P434H
c.1301C>A
1 paper
NM_012255.5
p.S448*
c.1343C>A
1 paper
NM_012255.5
p.S448*
c.1343C>G
1 paper
NM_012255.5
p.Q459H
c.1377A>T
1 paper
NM_012255.5
p.E463G
c.1388A>G
1 paper
NM_012255.5
p.R424G
c.1270A>G
1 paper
NM_012255.5
p.S473L
c.1418C>T
1 paper
NM_012255.5
p.G490E
c.1469G>A
1 paper
NM_012255.5
p.V527M
c.1579G>A
1 paper
NM_012255.5
p.A529T
c.1585G>A
1 paper
NM_012255.5
p.R535H
c.1604G>A
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