Varaico: Literature-Extracted Genetic Variants

YAP1

373 papers

RefSeq Summary

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development a...

Pfam Domains

TEADIR3aa 84–99UCSCOmega loop, TEAD interacting region 3

WWaa 173–202UCSCWW domain

WWaa 232–261UCSCWW domain

Gene Aliases

HGNC Name

Yes1 associated transcriptional regulator

HGNC Alias Symbols

YAP65; YAP-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001130145.3

p.P129P

c.387A>G

Surrounding Variants

1 paper

NM_001130145.3

p.P129L

c.386C>T

1 paper

NM_001130145.3

p.P129T

c.385C>A

1 paper

NM_001130145.3

p.S128F

c.383C>T

2 papers

NM_001130145.3

p.S131A

c.391T>G

1 paper

NM_001130145.3

p.S128A

c.382T>G

1 paper

NM_001130145.3

p.S127Y

c.380C>A

1 paper

NM_001130145.3

p.S127F

c.380C>T

1 paper

NM_001130145.3

p.S127P

c.379T>C

62 papers

NM_001130145.3

p.S127A

c.379T>G

1 paper

NM_001130145.3

p.H126N

c.376C>A

1 paper

NM_001130145.3

p.R124G

c.370C>G

2 papers

NM_001130145.3

p.R124*

c.370C>T