Varaico: Literature-Extracted Genetic Variants

YES1

106 papers

RefSeq Summary

This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity...

Pfam Domains

SH3_1aa 97–144UCSCSH3 domain

SH2aa 158–240UCSCSH2 domain

PK_Tyr_Ser-Thraa 277–526UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

YES proto-oncogene 1, Src family tyrosine kinase

HGNC Alias Symbols

c-yes; HsT441

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005433.4

p.M505V

c.1513A>G

Surrounding Variants

1 paper

NM_005433.4

p.H502L

c.1505A>T

1 paper

NM_005433.4

p.E499K

c.1495G>A

1 paper

NM_005433.4

p.Q495E

c.1483C>G

1 paper

NM_005433.4

p.P492L

c.1475C>T

1 paper

NM_005433.4

p.R487*

c.1459C>T

1 paper

NM_005433.4

p.L526F

c.1578G>T

1 paper

NM_005433.4

p.L526F

c.1578G>C

1 paper

NM_005433.4

p.R479H

c.1436G>A

2 papers

NM_005433.4

p.G475C

c.1423G>T

2 papers

NM_005433.4

p.Y537F

c.1610A>T

1 paper

NM_005433.4

p.G540E

c.1619G>A

1 paper

NM_005433.4

p.G475C

c.1423G>T