Varaico: Literature-Extracted Genetic Variants

YTHDC2

90 papers

RefSeq Summary

This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a commo...

Pfam Domains

R3Haa 44–104UCSCR3H domain

DEADaa 196–356UCSCDEAD/DEAH box helicase

Helicase_Caa 606–744UCSCHelicase conserved C-terminal domain

WHD_HA2aa 809–837UCSCHelicase associated domain (HA2), winged-helix

HA2_Caa 838–900UCSCHelicase associated domain (HA2), ratchet-like

OB_NTP_bindaa 971–1067UCSCOligonucleotide/oligosaccharide-binding (OB)-fold

Gene Aliases

HGNC Name

YTH N6-methyladenosine RNA binding protein C2

HGNC Alias Symbols

FLJ2194; FLJ10053; DKFZp564A186

Papers

RefSeq ID

Protein change

DNA change

1–12 of 90 variants

4 papers

NM_022828.5

p.L1409Q

c.4226T>A

3 papers

NM_022828.5

p.E317Q

c.949G>C

3 papers

NM_022828.5

p.D651H

c.1951G>C

3 papers

NM_022828.5

p.S652N

c.1955G>A

2 papers

NM_022828.5

p.S6C

c.16A>T

2 papers

NM_022828.5

p.R80Q

c.239G>A

2 papers

NM_022828.5

p.E185K

c.553G>A

2 papers

NM_022828.5

p.R242H

c.725G>A

2 papers

NM_022828.5

p.H312R

c.935A>G

2 papers

NM_022828.5

p.R321T

c.962G>C

2 papers

NM_022828.5

p.E377*

c.1129G>T

2 papers

NM_022828.5

p.P856R

c.2567C>G