Varaico: Literature-Extracted Genetic Variants

YTHDC2

90 papers

RefSeq Summary

This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a commo...

Pfam Domains

R3Haa 44–104UCSCR3H domain

DEADaa 196–356UCSCDEAD/DEAH box helicase

Helicase_Caa 606–744UCSCHelicase conserved C-terminal domain

WHD_HA2aa 809–837UCSCHelicase associated domain (HA2), winged-helix

HA2_Caa 838–900UCSCHelicase associated domain (HA2), ratchet-like

OB_NTP_bindaa 971–1067UCSCOligonucleotide/oligosaccharide-binding (OB)-fold

Gene Aliases

HGNC Name

YTH N6-methyladenosine RNA binding protein C2

HGNC Alias Symbols

FLJ2194; FLJ10053; DKFZp564A186

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_022828.5

p.R80Q

c.239G>A

Surrounding Variants

1 paper

NM_022828.5

p.L36_K37ins6

c.106_110ins18

1 paper

NM_022828.5

p.G16S

c.46G>A

1 paper

NM_022828.5

p.P12_A13ins2

c.36_37ins6

2 papers

NM_022828.5

p.S6C

c.16A>T

1 paper

NM_022828.5

p.G95R

c.283G>A

1 paper

NM_022828.5

p.G95R

c.283G>C

1 paper

NM_022828.5

p.K105N

c.315A>T

1 paper

NM_022828.5

p.T110I

c.329C>T