Varaico: Literature-Extracted Genetic Variants

YTHDC2

90 papers

RefSeq Summary

This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a commo...

Pfam Domains

R3Haa 44–104UCSCR3H domain

DEADaa 196–356UCSCDEAD/DEAH box helicase

Helicase_Caa 606–744UCSCHelicase conserved C-terminal domain

WHD_HA2aa 809–837UCSCHelicase associated domain (HA2), winged-helix

HA2_Caa 838–900UCSCHelicase associated domain (HA2), ratchet-like

OB_NTP_bindaa 971–1067UCSCOligonucleotide/oligosaccharide-binding (OB)-fold

Gene Aliases

HGNC Name

YTH N6-methyladenosine RNA binding protein C2

HGNC Alias Symbols

FLJ2194; FLJ10053; DKFZp564A186

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_022828.5

p.E374Q

c.1120G>C

Surrounding Variants

2 papers

NM_022828.5

p.E377*

c.1129G>T

1 paper

NM_022828.5

p.F422C

c.1265T>G

1 paper

NM_022828.5

p.E438A

c.1313A>C

1 paper

NM_022828.5

p.H479N

c.1435C>A

1 paper

NM_022828.5

p.D481V

c.1442A>T

1 paper

NM_022828.5

p.Q487L

c.1460A>T

1 paper

NM_022828.5

p.F324L

c.972T>A

1 paper

NM_022828.5

p.F324L

c.972T>G

1 paper

NM_022828.5

p.F324L

c.970T>C

1 paper

NM_022828.5

p.F324_S325delFs

c.970_974del5

2 papers

NM_022828.5

p.R321T

c.962G>C

3 papers

NM_022828.5

p.E317Q

c.949G>C