Varaico: Literature-Extracted Genetic Variants

YTHDC2

90 papers

RefSeq Summary

This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a commo...

Pfam Domains

R3Haa 44–104UCSCR3H domain

DEADaa 196–356UCSCDEAD/DEAH box helicase

Helicase_Caa 606–744UCSCHelicase conserved C-terminal domain

WHD_HA2aa 809–837UCSCHelicase associated domain (HA2), winged-helix

HA2_Caa 838–900UCSCHelicase associated domain (HA2), ratchet-like

OB_NTP_bindaa 971–1067UCSCOligonucleotide/oligosaccharide-binding (OB)-fold

Gene Aliases

HGNC Name

YTH N6-methyladenosine RNA binding protein C2

HGNC Alias Symbols

FLJ2194; FLJ10053; DKFZp564A186

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_022828.5

p.G680A

c.2039G>C

Surrounding Variants

1 paper

NM_022828.5

p.A679V

c.2036C>T

1 paper

NM_022828.5

p.R682Q

c.2045G>A

1 paper

NM_022828.5

p.E692G

c.2075A>G

1 paper

NM_022828.5

p.T653I

c.1958C>T

3 papers

NM_022828.5

p.S652N

c.1955G>A

3 papers

NM_022828.5

p.D651H

c.1951G>C

1 paper

NM_022828.5

p.E634K

c.1900G>A

1 paper

NM_022828.5

p.A537S

c.1609G>T

1 paper

NM_022828.5

p.G516V

c.1547G>T

1 paper

NM_022828.5

p.A515V

c.1544C>T

1 paper

NM_022828.5

p.H503Q

c.1509T>A

1 paper

NM_022828.5

p.H503Q

c.1509T>G