Varaico: Literature-Extracted Genetic Variants

YTHDC2

90 papers

RefSeq Summary

This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a commo...

Pfam Domains

R3Haa 44–104UCSCR3H domain

DEADaa 196–356UCSCDEAD/DEAH box helicase

Helicase_Caa 606–744UCSCHelicase conserved C-terminal domain

WHD_HA2aa 809–837UCSCHelicase associated domain (HA2), winged-helix

HA2_Caa 838–900UCSCHelicase associated domain (HA2), ratchet-like

OB_NTP_bindaa 971–1067UCSCOligonucleotide/oligosaccharide-binding (OB)-fold

Gene Aliases

HGNC Name

YTH N6-methyladenosine RNA binding protein C2

HGNC Alias Symbols

FLJ2194; FLJ10053; DKFZp564A186

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_022828.5

p.L1409Q

c.4226T>A

Surrounding Variants

2 papers

NM_022828.5

p.N1427insFs

c.4280dupA

1 paper

NM_022828.5

p.E1425fs

c.4273_4274fs

1 paper

NM_022828.5

p.H1341fs

c.4021_4022fs

1 paper

NM_022828.5

p.S1339C

c.4016C>G

1 paper

NM_022828.5

p.R1289Q

c.3866G>A

2 papers

NM_022828.5

p.P1282S

c.3844C>T

1 paper

NM_022828.5

p.R1247*

c.3739C>T

1 paper

NM_022828.5

p.P1222T

c.3664C>A