Varaico: Literature-Extracted Genetic Variants

ZC3H12A

103 papers

RefSeq Summary

ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.[suppl...

Pfam Domains

UBA_6aa 48–89UCSCUBA-like domain

RNase_Zc3h12aaa 134–290UCSCZc3h12a-like Ribonuclease NYN domain

Regnase_1_Caa 549–593UCSCEndoribonuclease Regnase 1/ ZC3H12 C-terminal domain

Gene Aliases

HGNC Name

zinc finger CCCH-type containing 12A

HGNC Alias Symbols

FLJ23231; MCPIP1; Regnase-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_025079.3

p.E37Q

c.109G>C

Surrounding Variants

1 paper

NM_025079.3

p.P34L

c.101C>T

3 papers

NM_025079.3

p.R33S

c.99G>C

3 papers

NM_025079.3

p.R33S

c.99G>T

4 papers

NM_025079.3

p.P32L

c.95C>T

1 paper

NM_025079.3

p.D24H

c.70G>C

1 paper

NM_025079.3

p.E23E

c.69G>A

1 paper

NM_025079.3

p.A13P

c.37G>C

1 paper

NM_025079.3

p.T63M

c.188C>T

1 paper

NM_025079.3

p.V10G

c.29T>G

1 paper

NM_025079.3

p.V68delFs

c.203_204delTC

1 paper

NM_025079.3

p.P4P

c.12C>A

1 paper

NM_025079.3

p.P4L

c.11C>T