Varaico: Literature-Extracted Genetic Variants

ZC3HAV1

172 papers

RefSeq Summary

This gene encodes a CCCH-type zinc finger protein. This antiviral protein inhibits viral replication by recruiting cellular RNA degradation machineries to degrade viral mRNAs. The encoded protein play...

Pfam Domains

HTH_53aa 5–66UCSCZap helix turn helix N-terminal domain

zf-CCCH_PARP12aa 71–117UCSCPARP12-like CCCH zinc finger tandem

zf-CCCH_8aa 143–170UCSCZinc-finger antiviral protein (ZAP) zinc finger domain 3

WWE_4aa 536–590UCSCWWE domain

WWEaa 607–682UCSCWWE domain

PARPaa 737–868UCSCPoly(ADP-ribose) polymerase catalytic domain

Gene Aliases

HGNC Name

zinc finger CCCH-type containing, antiviral 1

HGNC Alias Symbols

FLB6421; FLJ13288; MGC48898; ZC3HDC2; ZC3H2; PARP13; ARTD13

Papers

RefSeq ID

Protein change

DNA change

1–12 of 118 variants

6 papers

NM_020119.4

p.T851I

c.2552C>T

4 papers

NM_020119.4

p.Q701E

c.2101C>G

3 papers

NM_020119.4

p.C88R

c.262T>C

3 papers

NM_020119.4

p.Q620*

c.1858C>T

2 papers

NM_020119.4

p.M1T

c.2T>C

2 papers

NM_020119.4

p.T316P

c.946A>C

2 papers

NM_020119.4

p.R385C

c.1153C>T

2 papers

NM_020119.4

p.R577W

c.1729C>T

1 paper

NM_020119.4

p.V6A

c.17T>C

1 paper

NM_020119.4

p.V6E

c.17T>A

1 paper

NM_020119.4

p.T11A

c.31A>G

1 paper

NM_020119.4

p.T11T

c.33C>A