Varaico: Literature-Extracted Genetic Variants

ZC3HAV1

172 papers

RefSeq Summary

This gene encodes a CCCH-type zinc finger protein. This antiviral protein inhibits viral replication by recruiting cellular RNA degradation machineries to degrade viral mRNAs. The encoded protein play...

Pfam Domains

HTH_53aa 5–66UCSCZap helix turn helix N-terminal domain

zf-CCCH_PARP12aa 71–117UCSCPARP12-like CCCH zinc finger tandem

zf-CCCH_8aa 143–170UCSCZinc-finger antiviral protein (ZAP) zinc finger domain 3

WWE_4aa 536–590UCSCWWE domain

WWEaa 607–682UCSCWWE domain

PARPaa 737–868UCSCPoly(ADP-ribose) polymerase catalytic domain

Gene Aliases

HGNC Name

zinc finger CCCH-type containing, antiviral 1

HGNC Alias Symbols

FLB6421; FLJ13288; MGC48898; ZC3HDC2; ZC3H2; PARP13; ARTD13

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_020119.4

p.T851I

c.2552C>T

Surrounding Variants

1 paper

NM_020119.4

p.T856M

c.2567C>T

1 paper

NM_020119.4

p.M840V

c.2518A>G

1 paper

NM_020119.4

p.V839I

c.2515G>A

1 paper

NM_020119.4

p.F864F

c.2592C>T

1 paper

NM_020119.4

p.D834_A835insFs

c.2502_2503insA

1 paper

NM_020119.4

p.S872L

c.2615C>T

1 paper

NM_020119.4

p.V876I

c.2626G>A

1 paper

NM_020119.4

p.I818V

c.2452A>G

1 paper

NM_020119.4

p.E895A

c.2684A>C

1 paper

NM_020119.4

p.C899S

c.2695T>A

1 paper

NM_020119.4

p.C899S

c.2696G>C

1 paper

NM_020119.4

p.Y814Y

c.2442C>T