Varaico: Literature-Extracted Genetic Variants

ZC3HAV1

172 papers

RefSeq Summary

This gene encodes a CCCH-type zinc finger protein. This antiviral protein inhibits viral replication by recruiting cellular RNA degradation machineries to degrade viral mRNAs. The encoded protein play...

Pfam Domains

HTH_53aa 5–66UCSCZap helix turn helix N-terminal domain

zf-CCCH_PARP12aa 71–117UCSCPARP12-like CCCH zinc finger tandem

zf-CCCH_8aa 143–170UCSCZinc-finger antiviral protein (ZAP) zinc finger domain 3

WWE_4aa 536–590UCSCWWE domain

WWEaa 607–682UCSCWWE domain

PARPaa 737–868UCSCPoly(ADP-ribose) polymerase catalytic domain

Gene Aliases

HGNC Name

zinc finger CCCH-type containing, antiviral 1

HGNC Alias Symbols

FLB6421; FLJ13288; MGC48898; ZC3HDC2; ZC3H2; PARP13; ARTD13

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_020119.4

p.Y814Y

c.2442C>T

Surrounding Variants

1 paper

NM_020119.4

p.R791G

c.2371C>G

1 paper

NM_020119.4

p.A788V

c.2363C>T

1 paper

NM_020119.4

p.K783R

c.2348A>G

1 paper

NM_020119.4

p.W773Splc

c.2319-1G>C

1 paper

NM_020119.4

p.W773Splc

c.2319-26G>A

1 paper

NM_020119.4

p.H735L

c.2204A>T

1 paper

NM_020119.4

p.F720V

c.2158T>G

1 paper

NM_020119.4

p.K704N

c.2112G>T

1 paper

NM_020119.4

p.K704N

c.2112G>C

4 papers

NM_020119.4

p.Q701E

c.2101C>G

1 paper

NM_020119.4

p.I818V

c.2452A>G

1 paper

NM_020119.4

p.D834_A835insFs

c.2502_2503insA