Varaico: Literature-Extracted Genetic Variants

ZEB2

494 papers

RefSeq Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that...

Pfam Domains

zf-Di19aa 209–269UCSCDrought induced 19 protein (Di19), zinc-binding

zf-C2H2aa 282–304UCSCZinc finger, C2H2 type

zf-C2H2aa 310–331UCSCZinc finger, C2H2 type

zf-C2H2aa 999–1021UCSCZinc finger, C2H2 type

zf-C2H2aa 1055–1076UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger E-box binding homeobox 2

HGNC Previous Symbol

ZFHX1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014795.4

p.G1068C

c.3202G>T

Surrounding Variants

2 papers

NM_014795.4

p.G1068D

c.3203G>A

1 paper

NM_014795.4

p.S1067*

c.3200C>A

2 papers

NM_014795.4

p.S1067_G1068ins5

c.3199_3203ins15

1 paper

NM_014795.4

p.H1066fs

c.3196_3197fs

1 paper

NM_014795.4

p.S1069*

c.3206C>A

1 paper

NM_014795.4

p.S1069S

c.3207G>C

1 paper

NM_014795.4

p.R1063_S1065del3

c.3187_3194del9

1 paper

NM_014795.4

p.H1066Y

c.3196C>T

2 papers

NM_014795.4

p.S1065insFs

c.3195dupA

1 paper

NM_014795.4

p.H1066fs

c.3196_3197fs

1 paper

NM_014795.4

p.Y1070S

c.3209A>C

1 paper

NM_014795.4

p.Y1070*

c.3210C>G