Varaico: Literature-Extracted Genetic Variants

ZEB2

494 papers

RefSeq Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that...

Pfam Domains

zf-Di19aa 209–269UCSCDrought induced 19 protein (Di19), zinc-binding

zf-C2H2aa 282–304UCSCZinc finger, C2H2 type

zf-C2H2aa 310–331UCSCZinc finger, C2H2 type

zf-C2H2aa 999–1021UCSCZinc finger, C2H2 type

zf-C2H2aa 1055–1076UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger E-box binding homeobox 2

HGNC Previous Symbol

ZFHX1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014795.4

p.M949T

c.2846T>C

Surrounding Variants

2 papers

NM_014795.4

p.M949insFs

c.2845dupA

1 paper

NM_014795.4

p.M949fs

c.2845_2846fs

2 papers

NM_014795.4

p.Q951*

c.2851C>T

1 paper

NM_014795.4

p.F946delFs

c.2837_2838delAA

2 papers

NM_014795.4

p.R952T

c.2855G>C

11 papers

NM_014795.4

p.R953G

c.2857A>G

2 papers

NM_014795.4

p.R952delFs

c.2856delC

3 papers

NM_014795.4

p.R953fs

c.2857_2858fs

1 paper

NM_014795.4

p.A943P

c.2827G>C

3 papers

NM_014795.4

p.Y955*

c.2865C>G

3 papers

NM_014795.4

p.Y955*

c.2865C>A

6 papers

NM_014795.4

p.Q956*

c.2866C>T