Varaico: Literature-Extracted Genetic Variants

ZEB2

494 papers

RefSeq Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that...

Pfam Domains

zf-Di19aa 209–269UCSCDrought induced 19 protein (Di19), zinc-binding

zf-C2H2aa 282–304UCSCZinc finger, C2H2 type

zf-C2H2aa 310–331UCSCZinc finger, C2H2 type

zf-C2H2aa 999–1021UCSCZinc finger, C2H2 type

zf-C2H2aa 1055–1076UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger E-box binding homeobox 2

HGNC Previous Symbol

ZFHX1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014795.4

p.N718fs

c.2152_2153fs

Surrounding Variants

1 paper

NM_014795.4

p.N720fs

c.2158_2159fs

1 paper

NM_014795.4

p.S719_N720insFs

c.2157_2158dupTA

1 paper

NM_014795.4

p.P714P

c.2142G>A

5 papers

NM_014795.4

p.P714L

c.2141C>T

1 paper

NM_014795.4

p.T723K

c.2168C>A

2 papers

NM_014795.4

p.K713fs

c.2137_2138fs

2 papers

NM_014795.4

p.S712delFs

c.2136delG

6 papers

NM_014795.4

p.S726fs

c.2176_2177fs

1 paper

NM_014795.4

p.S726delFs

c.2176delA

1 paper

NM_014795.4

p.S726delFs

c.2177_2178delAG

4 papers

NM_014795.4

p.L727fs

c.2179_2180fs

9 papers

NM_014795.4

p.L727*

c.2180T>G