Varaico: Literature-Extracted Genetic Variants

ZEB2

494 papers

RefSeq Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that...

Pfam Domains

zf-Di19aa 209–269UCSCDrought induced 19 protein (Di19), zinc-binding

zf-C2H2aa 282–304UCSCZinc finger, C2H2 type

zf-C2H2aa 310–331UCSCZinc finger, C2H2 type

zf-C2H2aa 999–1021UCSCZinc finger, C2H2 type

zf-C2H2aa 1055–1076UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger E-box binding homeobox 2

HGNC Previous Symbol

ZFHX1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_014795.4

p.F687delFs

c.2061delA

Surrounding Variants

1 paper

NM_014795.4

p.F687fs

c.2059_2060fs

1 paper

NM_014795.4

p.F687fs

c.2059_2060fs

3 papers

NM_001171653.2

p.E662*

c.1984G>T

NM_014795.4

p.E686*

c.2056G>T

2 papers

NM_014795.4

p.Q685*

c.2053C>T

3 papers

NM_014795.4

p.W691*

c.2072G>A

2 papers

NM_014795.4

p.W691*

c.2073G>A

2 papers

NM_014795.4

p.F692fs

c.2074_2075fs

1 paper

NM_014795.4

p.F692F

c.2076T>C

1 paper

NM_014795.4

p.F692delFs

c.2076delA

1 paper

NM_014795.4

p.G682R

c.2044G>C

3 papers

NM_014795.4

p.Q694*

c.2080C>T

1 paper

NM_014795.4

p.V681M

c.2041G>A