Varaico: Literature-Extracted Genetic Variants

ZEB2

494 papers

RefSeq Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that...

Pfam Domains

zf-Di19aa 209–269UCSCDrought induced 19 protein (Di19), zinc-binding

zf-C2H2aa 282–304UCSCZinc finger, C2H2 type

zf-C2H2aa 310–331UCSCZinc finger, C2H2 type

zf-C2H2aa 999–1021UCSCZinc finger, C2H2 type

zf-C2H2aa 1055–1076UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger E-box binding homeobox 2

HGNC Previous Symbol

ZFHX1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014795.4

p.K653R

c.1958A>G

Surrounding Variants

6 papers

NM_014795.4

p.Y652*

c.1956C>G

9 papers

NM_014795.4

p.Y652*

c.1956C>A

2 papers

NM_014795.4

p.H655Q

c.1965C>G

1 paper

NM_014795.4

p.H655Q

c.1965C>A

3 papers

NM_014795.4

p.M656fs

c.1966_1967fs

3 papers

NM_014795.4

p.M656delFs

c.1966_1967delAT

3 papers

NM_014795.4

p.I649delFs

c.1946delA

4 papers

NM_014795.4

p.I649fs

c.1945_1946fs

2 papers

NM_014795.4

p.P648delFs

c.1944delG

1 paper

NM_014795.4

p.P648fs

c.1942_1943fs

1 paper

NM_014795.4

p.L659F

c.1975C>T

1 paper

NM_014795.4

p.T646I

c.1937C>T