Varaico: Literature-Extracted Genetic Variants

ZEB2

494 papers

RefSeq Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that...

Pfam Domains

zf-Di19aa 209–269UCSCDrought induced 19 protein (Di19), zinc-binding

zf-C2H2aa 282–304UCSCZinc finger, C2H2 type

zf-C2H2aa 310–331UCSCZinc finger, C2H2 type

zf-C2H2aa 999–1021UCSCZinc finger, C2H2 type

zf-C2H2aa 1055–1076UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger E-box binding homeobox 2

HGNC Previous Symbol

ZFHX1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014795.4

p.G449delFs

c.1347delC

Surrounding Variants

1 paper

NM_014795.4

p.F450I

c.1348T>A

1 paper

NM_014795.4

p.G449E

c.1346G>A

1 paper

NM_014795.4

p.P451S

c.1351C>T

1 paper

NM_014795.4

p.L448R

c.1343T>G

2 papers

NM_014795.4

p.T452fs

c.1354_1355fs

1 paper

NM_014795.4

p.T452A

c.1354A>G

2 papers

NM_014795.4

p.P451delFs

c.1353delG

1 paper

NM_014795.4

p.T452insFs

c.1354dupA

2 papers

NM_014795.4

p.L447fs

c.1339_1340fs

1 paper

NM_014795.4

p.P446insFs

c.1337dupC

1 paper

NM_014795.4

p.M453I

c.1359G>T

1 paper

NM_014795.4

p.M453I

c.1359G>C